Prescribing information

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Sycrest (asenapine) is the first tetracyclic antipsychotic therapy for the treatment of moderate to severe manic episodes associated with bipolar I disorder in adults.

Sycrest is the first tetracyclic antipsychotic with a unique receptor profile:

  • Sycrest demonstrates rapid efficacy as early as day 23
  • Treatment response with Sycrest can be predicted early10
  • Sycrest demonstrates sustained efficacy at 12 weeks 7
  • Sycrest has a lower potential for long term weight gain and a lower impact on metabolic profile compared to olanzapine8